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Life Insurers Are Testing Biological Age. Federal Law Does Not Fully Protect You From That

Insurers have begun exploring epigenetic testing, the same kind of biological age technology increasingly discussed in longevity medicine, as a tool for evaluating life insurance applicants. At least one major life insurer has already partnered with a genomics company to

3 min read

The Bacteria in Your Mouth May Be Talking to Your Brain. Researchers Are Taking It Seriously

Gum disease has long been treated as a localized dental problem, something to manage with better brushing and regular cleanings, separate from the rest of a person's health. That framing is looking increasingly incomplete. Researchers have identified a

3 min read

Astronauts Are a Compressed Model of Aging, With One Genuinely Strange Twist

A few months in orbit produces changes in healthy, carefully screened astronauts that echo several recognized hallmarks of aging, shifts in stem cell function, gene expression, immune activity, and the gut microbiome, all compressed into a fraction of the time

3 min read

Bariatric Surgery Still Outperforms GLP-1 Drugs, and the Reason Why Matters

GLP-1 drugs have dominated the conversation about obesity treatment for the past several years, but a large real-world comparison spanning more than thirty studies and over four hundred thousand patients found something worth sitting with: metabolic and bariatric

3 min read

The First "Three-Parent" Babies Are Healthy, With One Complication Worth Understanding

Eight children born in the United Kingdom using a technique that combines genetic material from three people are now the subject of the first published, peer-reviewed results on how the approach actually performs in practice. The technique, mitochondrial donation,

3 min read

Young Blood Plasma Therapy Sounds Like Science Fiction. The FDA Already Weighed In

A striking finding in aging mice, that exposure to young blood could improve muscle repair, brain function, and even extend lifespan, has quietly powered an entire corner of the longevity industry for over a decade. Clinics offer young donor plasma

3 min read

Long COVID Has Never Had a Diagnostic Test. Multiple Candidates Are Finally Emerging

Since long COVID first emerged as a recognized condition, it has been diagnosed almost entirely by exclusion, a doctor ruling out other explanations for a patient's fatigue, breathlessness, or exercise intolerance rather than confirming the condition with any

3 min read

Stem Cell Injections for Knee Arthritis Are Advancing to Phase III, With One Real Limitation

A stem cell therapy for knee osteoarthritis just secured a large new round of funding to push it into a pivotal Phase III trial, the last major step before a treatment can seek approval. The therapy uses mesenchymal stem cells

3 min read

A Vagus Nerve Implant Just Passed Its Biggest Test for Rheumatoid Arthritis

A small device implanted on the vagus nerve, rather than a drug, just cleared its most rigorous test yet as a treatment for rheumatoid arthritis. In a pivotal, sham-controlled trial of 242 patients who had not responded well to

3 min read

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