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Long COVID Has Never Had a Diagnostic Test. Multiple Candidates Are Finally Emerging

Since long COVID first emerged as a recognized condition, it has been diagnosed almost entirely by exclusion, a doctor ruling out other explanations for a patient's fatigue, breathlessness, or exercise intolerance rather than confirming the condition with any

3 min read

Stem Cell Injections for Knee Arthritis Are Advancing to Phase III, With One Real Limitation

A stem cell therapy for knee osteoarthritis just secured a large new round of funding to push it into a pivotal Phase III trial, the last major step before a treatment can seek approval. The therapy uses mesenchymal stem cells

3 min read

A Vagus Nerve Implant Just Passed Its Biggest Test for Rheumatoid Arthritis

A small device implanted on the vagus nerve, rather than a drug, just cleared its most rigorous test yet as a treatment for rheumatoid arthritis. In a pivotal, sham-controlled trial of 242 patients who had not responded well to

3 min read

What Actually Happens After a Longevity Clinic's Full-Body Scan Finds Something

The longevity clinic industry has grown quickly, with an estimated eight hundred clinics now operating across the United States, many selling extensive imaging and biomarker testing packages as a form of proactive health insurance. Top-tier concierge memberships can run

3 min read

Stem Cell-Derived Neurons Are Showing Real, Multi-Year Benefit for Parkinson's Disease

Parkinson's disease progresses because a specific population of brain cells that produce dopamine gradually dies off, and no existing treatment replaces those cells, only manages the resulting symptoms. Two independent research programs are now testing a more direct

3 min read

Rapamycin Is Longevity Medicine's Most Popular Off-Label Drug. The Trials Still Do Not Back That Up

Rapamycin, an old immunosuppressant drug repurposed by longevity clinics as a low-dose anti-aging treatment, has become one of the most widely prescribed off-label longevity interventions available today. The theory behind it is genuinely serious science, it targets

3 min read

A Personalized Cancer Vaccine Is Delivering Real Multi-Year Results, With One Important Caveat

Personalized mRNA cancer vaccines, built from a patient's own tumor rather than mass-produced, have moved past their early proof-of-concept stage and are now generating results that stretch out for years. Updated data on a pancreatic

3 min read

A Blood Test Can Now Help Diagnose Alzheimer's. It Is Not a Screening Test for Healthy People

For years, confirming whether someone's memory problems were actually caused by Alzheimer's disease meant an expensive brain scan or an invasive spinal tap. That changed with the clearance of blood tests measuring a protein called p-

3 min read

The Unglamorous Fix That Is Quietly Expanding the Organ Transplant Supply

For decades, a donated organ traveled from operating room to operating room the same simple way: packed on ice, racing against a clock before the tissue deteriorated too far to use. That basic method is now being replaced at many

3 min read

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